Antimicrobial Hydrogels: Potential Materials for Medical Application

doi:10.1002/smll.202304047

IR > 石油化工学院

	Antimicrobial Hydrogels: Potential Materials for Medical Application
	Li, Yanni; Han, Yujia; Li, Hongxia; Niu, Xiaohui; Zhang, Deyi; Wang, Kunjie
	2023-09-26
发表期刊	SMALL
ISSN	1613-6810
卷号	20 期号:5
摘要	Microbial infections based on drug-resistant pathogenic organisms following surgery or trauma and uncontrolled bleeding are the main causes of increased mortality from trauma worldwide. The prevalence of drug-resistant pathogens has led to a significant increase in medical costs and poses a great threat to the normal life of people. This is an important issue in the field of biomedicine, and the emergence of new antimicrobial materials hydrogels holds great promise for solving this problem. Hydrogel is an important material with good biocompatibility, water absorption, oxygen permeability, adhesion, degradation, self-healing, corrosion resistance, and controlled release of drugs as well as structural diversity. Bacteria-disturbing hydrogels have important applications in the direction of surgical treatment, wound dressing, medical device coating, and tissue engineering. This paper reviews the classification of antimicrobial hydrogels, the current status of research, and the potential of antimicrobial hydrogels for one application in biomedicine, and analyzes the current research of hydrogels in biomedical applications from five aspects: metal-loaded hydrogels, drug-loaded hydrogels, carbon-material-loaded hydrogels, hydrogels with fixed antimicrobial activity and biological antimicrobial hydrogels, and provides an outlook on the high antimicrobial activity, biodegradability, biocompatibility, injectability, clinical applicability and future development prospects of hydrogels in this field. Antibacterial hydrogels generally kill bacteria by disrupting cellular material transport, intracellular proteins, cell walls, reactive oxygen species and DNA. Due to the different properties of antimicrobial hydrogels of different compositions, their fields of application have expanded considerably. This also shows their great potential for biomedical applicationsimage
关键词	antibacterial hydrogel biomedical application classification development prospect research status
DOI	10.1002/smll.202304047
收录类别	SCIE ; EI
语种	英语
资助项目	This work was supported by the National Nature Science Foundations of China (Grants No. 22065021), the Key Research Program of Gansu Province (21YF5GA076), the Province Nature Science Foundations of Gansu (Grants No. 21JR7RA213), Innovation and Entrepreneu [22065021]; National Nature Science Foundations of China [21YF5GA076]; Key Research Program of Gansu Province [21JR7RA213]; Province Nature Science Foundations of Gansu [2022-RC-33]; Innovation and Entrepreneurship Talent Project of Lanzhou; Hongliu Outstanding Youth Teacher Cultivate Project of Lanzhou University of Technology and Hongliu Excellent Youth Teacher Cultivate Project of Lanzhou University of Technology
WOS研究方向	Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
WOS类目	Chemistry, Multidisciplinary ; Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter
WOS记录号	WOS:001070770800001
出版者	WILEY-V C H VERLAG GMBH
EI入藏号	20233914805659
EI主题词	Hydrogels
EI分类号	461.1 Biomedical Engineering ; 461.6 Medicine and Pharmacology ; 461.8 Biotechnology ; 461.9 Biology ; 461.9.1 Immunology ; 539.1 Metals Corrosion ; 801.2 Biochemistry ; 801.3 Colloid Chemistry ; 802.3 Chemical Operations ; 804 Chemical Products Generally
原始文献类型	Review;Early Access
EISSN	1613-6829
引用统计	被引频次[WOS]：0 [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://ir.lut.edu.cn/handle/2XXMBERH/166462
专题	石油化工学院
通讯作者	Wang, Kunjie
作者单位	Lanzhou Univ Technol, Coll Petrochem Technol, Lanzhou 730050, Peoples R China
第一作者单位	石油化工学院
通讯作者单位	石油化工学院
第一作者的第一单位	石油化工学院
推荐引用方式 GB/T 7714	Li, Yanni,Han, Yujia,Li, Hongxia,et al. Antimicrobial Hydrogels: Potential Materials for Medical Application[J]. SMALL,2023,20(5).
APA	Li, Yanni,Han, Yujia,Li, Hongxia,Niu, Xiaohui,Zhang, Deyi,&Wang, Kunjie.(2023).Antimicrobial Hydrogels: Potential Materials for Medical Application.SMALL,20(5).
MLA	Li, Yanni,et al."Antimicrobial Hydrogels: Potential Materials for Medical Application".SMALL 20.5(2023).