Insights into the Structures, Inhibitors, and Improvement Strategies of Glucose Oxidase

doi:10.3390/ijms23179841

	Insights into the Structures, Inhibitors, and Improvement Strategies of Glucose Oxidase
	Wang, Fan 1; Chen, Xiaona 1,2; Wang, Yonggang2 ; Li, Xing 1; Wan, Minglai 1,2; Zhang, Ge 1; Leng, Feifan2 ; Zhang, Haibo 1
	2022-09
发表期刊	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
卷号	23 期号:17
摘要	Glucose oxidase, which uses molecular oxygen as an electron acceptor to specifically catalyze the conversion of beta-d-glucose to gluconic acid and hydrogen peroxide (H2O2), has been considered an important enzyme in increasing environmental sustainability and food security. However, achieving the high yield, low price and high activity required for commercial viability remains challenging. In this review, we first present a brief introduction, looking at the sources, characteristics, catalytic process, and applications of glucose oxidase. Then, the predictive structures of glucose oxidase from two different sources are comparatively discussed. We summarize the inhibitors of glucose oxidase. Finally, we highlight how the production of glucose oxidase can be improved by optimizing the culture conditions and microbial metabolic engineering.
关键词	glucose oxidase structures inhibitors yield improvement
DOI	10.3390/ijms23179841
收录类别	SCIE
语种	英语
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry
WOS类目	Biochemistry & Molecular Biology ; Chemistry, Multidisciplinary
WOS记录号	WOS:000852508900001
出版者	MDPI
来源库	WOS
引用统计	被引频次：1[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://ir.lut.edu.cn/handle/2XXMBERH/159836
专题	生命科学与工程学院
通讯作者	Zhang, Haibo
作者单位	1.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Qingdao 266101, Peoples R China; 2.Lanzhou Univ Technol, Sch Life Sci & Engn, Lanzhou 730050, Peoples R China
推荐引用方式 GB/T 7714	Wang, Fan,Chen, Xiaona,Wang, Yonggang,et al. Insights into the Structures, Inhibitors, and Improvement Strategies of Glucose Oxidase[J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2022,23(17).
APA	Wang, Fan.,Chen, Xiaona.,Wang, Yonggang.,Li, Xing.,Wan, Minglai.,...&Zhang, Haibo.(2022).Insights into the Structures, Inhibitors, and Improvement Strategies of Glucose Oxidase.INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,23(17).
MLA	Wang, Fan,et al."Insights into the Structures, Inhibitors, and Improvement Strategies of Glucose Oxidase".INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 23.17(2022).