Fusiform-like metal-organic framework for enantioselective discrimination of tryptophan enantiomers

doi:10.1016/j.electacta.2022.140409

IR > 石油化工学院

	Fusiform-like metal-organic framework for enantioselective discrimination of tryptophan enantiomers
	Li, Hongxia; Wang, Letong; Yan, Simeng; Chen, Jinliang; Zhang, Mengmeng; Zhao, Rui; Niu, Xiaohui; Wang, Kunjie
	2022-07-01
发表期刊	Electrochimica Acta
ISSN	0013-4686
卷号	419
摘要	Construction of chiral electrochemical sensors for stereoselective recognition is of great significance in medicine and pharmacy. Compared with traditional chiral recognition materials, metal organic frameworks (MOFs) are undoubtedly a new type of materials for chiral recognition. Here, we report a novel MOFs structure (Phe-Cu-PTA) that formed by the metal ion Cu2+ and organic ligands [1.10-Pheanthroline (Phe), Terephthalic acid (PTA)], which was used to distinguish L-tryptophan and D-tryptophan (L/D-Trp) enantiomers. Differential pulse voltammetry (DPV) test results showed the ability of the Phe-Cu-PTA to recognize the Trp-enantiomers. Owing to the different steric configuration of the L/D-Trp-enantiomers, host (MOFs)-guest (Trp-isomers) interactions are different for L/D-Trp, the peak current values of L-Trp-and D-Trp-are obviously different, thereby effectively distinguishing the Trp-isomers. The results demonstrated that the developed MOFs (Phe-Cu-PTA) showed significantly higher binding force toward D-Trp-than L-Trp. Therefore, the proposed electrochemical chiral interface can be considered as a potential platform for enantiomeric recognition of chiral compounds. © 2022 Elsevier Ltd
关键词	Crystalline materials Electrochemical sensors Enantiomers Ligands Medicine Metal ions Metal-Organic Frameworks Metals Organometallics Voltammetry Chiral recognition D-tryptophan Enantioselective discrimination Framework structures L-tryptophan Ligand exchanges Metalorganic frameworks (MOFs) Stereoselective recognition Terephthalic acids Tryptophan enantiomers
DOI	10.1016/j.electacta.2022.140409
收录类别	EI ; SCIE
语种	英语
WOS研究方向	Electrochemistry
WOS类目	Electrochemistry
WOS记录号	WOS:000807364400003
出版者	Elsevier Ltd
EI入藏号	20221812056926
EI主题词	Amino acids
EI分类号	461.6 Medicine and Pharmacology ; 531.1 Metallurgy ; 732.2 Control Instrumentation ; 801 Chemistry ; 801.4 Physical Chemistry ; 801.4.1 Electrochemistry ; 804.1 Organic Compounds ; 933.1 Crystalline Solids
来源库	WOS
引用统计	被引频次：9[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://ir.lut.edu.cn/handle/2XXMBERH/158454
专题	石油化工学院
通讯作者	Wang, Kunjie
作者单位	Lanzhou Univ Technol, Sch Petrochem Engn, Lanzhou 730050, Peoples R China
第一作者单位	兰州理工大学
通讯作者单位	兰州理工大学
第一作者的第一单位	兰州理工大学
推荐引用方式 GB/T 7714	Li, Hongxia,Wang, Letong,Yan, Simeng,et al. Fusiform-like metal-organic framework for enantioselective discrimination of tryptophan enantiomers[J]. Electrochimica Acta,2022,419.
APA	Li, Hongxia.,Wang, Letong.,Yan, Simeng.,Chen, Jinliang.,Zhang, Mengmeng.,...&Wang, Kunjie.(2022).Fusiform-like metal-organic framework for enantioselective discrimination of tryptophan enantiomers.Electrochimica Acta,419.
MLA	Li, Hongxia,et al."Fusiform-like metal-organic framework for enantioselective discrimination of tryptophan enantiomers".Electrochimica Acta 419(2022).