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Antitumor activity of different fractions of Cynanchum komarocii in vitro | |
Pu, Xiuying![]() | |
2014 | |
会议名称 | 2013 International Conference on Human Health and Medical Engineering, HHME 2013 |
会议录名称 | WIT Transactions on Biomedicine and Health
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卷号 | 18 |
页码 | 731-735 |
会议日期 | December 7, 2013 - December 8, 2013 |
会议地点 | Wuhan, China |
出版者 | WITPress |
摘要 | The antitumor activity of Cynanchum komarovii has not been previously examined in vitro system. The aim of this study was to evaluate the antitumor potential of C. komarovii by studying in vitro antitumor activity of the different fractions extract. The proliferation inhibition rate and IC50 of HepG2 cells in vitro were investigated by the MTT assay of the different fractions of C. komarovii. Our study revealed that the petroleum ether, chloroform, ethyl acetate, acetone, and 70% ethanol extract of C. komarovii showed significant antitumor activity towards HepG2 cells, and the proliferation inhibition rates, respectively were 63.84%, 64.18%, 63.00%, 74.80%, and 59.60% in the 1000 μg/mL of extract and the IC50 values were 459.88, 388.87, 399.27, 196.66, and 289.17 μg/mL, respectively. It indicated that acetone parts had better inhibit growth effect on HepG2 cells. © 2014 WIT Press. |
关键词 | Biomedical engineering Anti-tumor activities Anti-tumors Cynanchum komarocii Ethanol extract In-vitro MTT Petroleum ether Proliferation inhibition |
DOI | 10.2495/HHME130432 |
收录类别 | EI |
语种 | 英语 |
EI入藏号 | 20143218035764 |
EI主题词 | Acetone |
ISSN | 17433525 |
来源库 | Compendex |
分类代码 | 461.1 Biomedical Engineering - 804.1 Organic Compounds |
引用统计 | 无
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文献类型 | 会议论文 |
条目标识符 | https://ir.lut.edu.cn/handle/2XXMBERH/117371 |
专题 | 生命科学与工程学院 |
作者单位 | Life Science and Engineering College, Lanzhou University of Technology, Lanzhou, China |
第一作者单位 | 兰州理工大学 |
推荐引用方式 GB/T 7714 | Pu, Xiuying,Wang, Hengrui,Yu, Shuang,et al. Antitumor activity of different fractions of Cynanchum komarocii in vitro[C]:WITPress,2014:731-735. |
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