Deferring senile effect of polysaccharides from Angelica and Astragalus on aging mice
Xiuying, Pu1; Yan, Li1; Liye, Zhou2
2011
会议名称2011 International Conference on Human Health and Biomedical Engineering, HHBE 2011
会议录名称Proceedings 2011 International Conference on Human Health and Biomedical Engineering, HHBE 2011
页码289-292
会议日期August 19, 2011 - August 22, 2011
会议地点Jilin, China
出版者IEEE Computer Society
摘要Angelica and Astragalus, Chinese herbal medicine, are used as immunostimulants for enriching the blood, anti-tumor and antioxidation effects. However, the synergistic mechanisms of antioxidant effect have long been the object of intensive study. We investigated the deferring senile effect of AAP on aging mice by determination of the contents of monoamine oxidase (MAO) in brain, hydroxyproline (Hyp) in skin, hydrogen peroxide (H2O 2) in serum, glutathione peroxidase (GSH-PX) and xanthine oxidase (XOD) in liver tissue and immunity organs index. The obtained results showed that AAP decreased significantly the content of MAO and H2O 2, and enhanced the concentrations of Hyp, GSH-PX and XOD in vivo. No significant differences were found when compared with those of vitamin E. Additionally, AAP could increase immunity organs index. These results demonstrated that AAP had significant deferring senile effect on the aging mice. These changes may be the important mechanisms to prevent mice from aging. © 2011 IEEE.
关键词Antioxidants Biomedical engineering Hydroxyproline Medicine Plants (botany) Aging mouse Antioxidation effects Astragalus polysaccharides Chinese herbal medicines Glutathione peroxidase GSH-PX Immune organs Synergistic mechanism
DOI10.1109/HHBE.2011.6027955
收录类别EI
语种英语
EI入藏号20114214427900
EI主题词Mammals
来源库Compendex
分类代码461 Bioengineering and Biology - 803 Chemical Agents and Basic Industrial Chemicals - 804 Chemical Products Generally
引用统计
文献类型会议论文
条目标识符https://ir.lut.edu.cn/handle/2XXMBERH/116672
专题生命科学与工程学院
作者单位1.School of Life Science and Engineering, Lanzhou University of Technology, Lanzhou, China;
2.Grassland College, Inner Mongolia University for the Nationalities, Tongliao, China
第一作者单位生命科学与工程学院
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Xiuying, Pu,Yan, Li,Liye, Zhou. Deferring senile effect of polysaccharides from Angelica and Astragalus on aging mice[C]:IEEE Computer Society,2011:289-292.
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