Synthesis, Crystal Structure and Biological Evaluation of 6΄-Chloro-4΄-methylene-3H spiro[isobenzofuran-1,3΄-isochroman]

doi:10.14102/j.cnki.0254-5861.2011-2030

	Synthesis, Crystal Structure and Biological Evaluation of 6΄-Chloro-4΄-methylene-3Hspiro[isobenzofuran-1,3΄-isochroman]
	Pu Xiu-Ying1 ; Xu Wen-Jun 1,2; Yi Yun-Peng 2; Li Hao-Wen 1; Liang Jian-Ping 2; Hao Bao-Cheng 2
	2019-01
发表期刊	Chinese J. Struct. Chem.
ISSN	0254-5861
卷号	38 期号:1 页码:89-94
摘要	The title compound 6΄-chloro-4΄-methylene-3H-spiro [isoben zofura-1,3΄-isochroman], C17H13ClO2, was prepared and characterized by IR, NMR, HRMS and single-crystal X-ray diffraction. This compound has a bisbenzannulated [5,5]-spiroketals skeleton. It crystallizes in orthorhombic, space group P212121 with a = 13.383(3), b = 7.6120(17), c = 13.793(3) Å, Z = 4, Dc = 1.275 g/cm3, µ = 0.28 mm–1, F(000) = 592, wR = 0.1443 and R = 0.0557. The preliminary biological test showed that the title compound has good anti-bacterial activities in vitro.
关键词	3H-spiro[isobenzofura-1,3΄-isochroman], single-crystal structure, anti-bacterial
学科门类	理学
DOI	10.14102/j.cnki.0254-5861.2011-2030
收录类别	SCI
语种	英语
资助项目	Agricultural Science and Technology Innovation Program (ASTIP)[CAASASTIP-2014-LIHPS-04]
WOS研究方向	Chemistry ; Crystallography
WOS类目	Chemistry, Inorganic & Nuclear ; Crystallography
WOS记录号	WOS:000464311000010
出版者	CHINESE JOURNAL STRUCTURAL CHEMISTRY
引用统计	被引频次[WOS]：0 [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://ir.lut.edu.cn/handle/2XXMBERH/110674
专题	生命科学与工程学院
通讯作者	Pu Xiu-Ying; Hao Bao-Cheng
作者单位	1.Lanzhou Univ Technol, Sch Life Sci & Engn, Lanzhou 730050, Gansu, Peoples R China; 2.Minist Agr, Inst Husb & Pharmaceut Sci CAAS, Key Lab Vet Pharmaceut Dev, Key Lab New Anim Drug Project Gansu Prov, Lanzhou 730050, Gansu, Peoples R China
第一作者单位	生命科学与工程学院
通讯作者单位	生命科学与工程学院
第一作者的第一单位	生命科学与工程学院
推荐引用方式 GB/T 7714	Pu Xiu-Ying,Xu Wen-Jun,Yi Yun-Peng,et al. Synthesis, Crystal Structure and Biological Evaluation of 6΄-Chloro-4΄-methylene-3Hspiro[isobenzofuran-1,3΄-isochroman][J]. Chinese J. Struct. Chem.,2019,38(1):89-94.
APA	Pu Xiu-Ying,Xu Wen-Jun,Yi Yun-Peng,Li Hao-Wen,Liang Jian-Ping,&Hao Bao-Cheng.(2019).Synthesis, Crystal Structure and Biological Evaluation of 6΄-Chloro-4΄-methylene-3Hspiro[isobenzofuran-1,3΄-isochroman].Chinese J. Struct. Chem.,38(1),89-94.
MLA	Pu Xiu-Ying,et al."Synthesis, Crystal Structure and Biological Evaluation of 6΄-Chloro-4΄-methylene-3Hspiro[isobenzofuran-1,3΄-isochroman]".Chinese J. Struct. Chem. 38.1(2019):89-94.