Preparation of Glutathione Molecularly Imprinted Polymer Microspheres by Reversed Phase Suspension Polymerization

doi:10.1080/03602559.2014.974277

IR > 研究生院

	Preparation of Glutathione Molecularly Imprinted Polymer Microspheres by Reversed Phase Suspension Polymerization
	Huo, Ting 1,2; Chen, Zhenbin1,2 ; Wang, Meng 1,2; Long, Jiapeng 1,2; Liu, Xiaojiao 1,2; Du, Xueyan1,2
	2015-06-23
发表期刊	POLYMER-PLASTICS TECHNOLOGY AND ENGINEERING
ISSN	0360-2559
卷号	54 期号:9 页码:889-898
摘要	Molecularly imprinted polymer microspheres (MIPMs) for Glutathione had been prepared by the reversed phase suspension polymerization method; MIPMs were synthesized by using acrylamide and N-vinyl pyrrolidone as functional monomers. N,N'-methylenebisacrylamide and dimethyl diallyl ammonium chloride were the cross-linkers and H2O2 and Vc were redox initiators, Span-80 was the surfactant used and cyclohexane was the oil phase. Our work can provide a method to obtain ball MIPMs, and in this way, the destruction of acting sites because powdery MIPMs could be avoided. Moreover, the low concentration of cross-linker results in imprinted sites not being formed during the reversed phase suspension polymerization. The double cross-linkers not only solved this problem, but they also enlarged the selection range of the template, monomer and cross-linker. Simultaneously, there's obviously a significant amount of synergy between the two cross-linkers that perhaps improve the adsorption capacity and selectivity. The conditions were investigated and optimized, and the optimum conditions were obtained as follows: the ratio of n(AM)/n(NVP) was 2; the optimum temperature and time were 50 degrees C and 4.5h; and, the dosage of GSH, DMDAAC and Vc were 0.8g, 14g and 0.023g, respectively, under the optimum conditions, GSH-MIPM was prepared and showed the adsorption capacity was 75mg center dot g(-1). Also, based on the samples prepared at the starting process and under optimal conditions, the adsorption kinetics and adsorption isotherm were investigated and analyzed, respectively.
关键词	Molecular imprinting Glutathione Adsorption capacity Reversed phase suspension polymerization
DOI	10.1080/03602559.2014.974277
收录类别	SCI ; SCIE
语种	英语
资助项目	National Natural Science Foundation, China[51061009] ; Doctorial Program Funds of the Lanzhou University of Technology[SB01200806]
WOS研究方向	Polymer Science
WOS类目	Polymer Science
WOS记录号	WOS:000355645800002
出版者	TAYLOR & FRANCIS INC
EI入藏号	20152400931721
EI主题词	Suspensions (fluids)
EI分类号	461.9 Biology - 802.3 Chemical Operations - 804 Chemical Products Generally - 804.1 Organic Compounds - 815.2 Polymerization
引用统计	被引频次：5[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://ir.lut.edu.cn/handle/2XXMBERH/34034
专题	研究生院材料科学与工程学院省部共建有色金属先进加工与再利用国家重点实验室
通讯作者	Chen, Zhenbin
作者单位	1.Lanzhou Univ Technol, State Key Lab Adv Proc & Recycling Nonferrous Met, Lanzhou 730050, Gansu, Peoples R China; 2.Lanzhou Univ Technol, Sch Mat Sci & Engn, Lanzhou 730050, Gansu, Peoples R China
第一作者单位	省部共建有色金属先进加工与再利用国家重点实验室; 材料科学与工程学院
通讯作者单位	省部共建有色金属先进加工与再利用国家重点实验室; 材料科学与工程学院
第一作者的第一单位	省部共建有色金属先进加工与再利用国家重点实验室
推荐引用方式 GB/T 7714	Huo, Ting,Chen, Zhenbin,Wang, Meng,et al. Preparation of Glutathione Molecularly Imprinted Polymer Microspheres by Reversed Phase Suspension Polymerization[J]. POLYMER-PLASTICS TECHNOLOGY AND ENGINEERING,2015,54(9):889-898.
APA	Huo, Ting,Chen, Zhenbin,Wang, Meng,Long, Jiapeng,Liu, Xiaojiao,&Du, Xueyan.(2015).Preparation of Glutathione Molecularly Imprinted Polymer Microspheres by Reversed Phase Suspension Polymerization.POLYMER-PLASTICS TECHNOLOGY AND ENGINEERING,54(9),889-898.
MLA	Huo, Ting,et al."Preparation of Glutathione Molecularly Imprinted Polymer Microspheres by Reversed Phase Suspension Polymerization".POLYMER-PLASTICS TECHNOLOGY AND ENGINEERING 54.9(2015):889-898.