Fluorescent glutathione probe based on MnO2-Si quantum dots nanocomposite directly used for intracellular glutathione imaging | |
Ma, Hong1,2; Li, Xinran1,2; Liu, Xiaoyu1,2,3; Deng, Min1,2; Wang, Xudong1,2; Iqbal, Anam1,2; Liu, Weisheng1,2; Qin, Wenwu1,2 | |
2018-02 | |
发表期刊 | SENSORS AND ACTUATORS B-CHEMICAL |
卷号 | 255页码:1687-1693 |
摘要 | A highly sensitive glutathione probe based on silicon quantum dots (SiQDs) modified with MnO2 nanosheets has been developed. A strong reduction of the blue fluorescence of the SiQDs happened due to the surface energy transfer (SET) from SiQDs to the deposited MnO2. Fluorescence can be restored in the presence of glutathione on account of the MnO2 nanosheets are reduced. A fluorometric glutathione detection assay with a low detection limit (153 nM, at an S/N ratio of 3) can be designed via this method. It can be applied to directly determine GSH in living cells. A significant blue fluorescence image is produced in the cytosol of the cell and the fluorescence disappears while the cells treated with scavenger of GSH. (C) 2017 Elsevier B.V. All rights reserved. |
关键词 | Silicon quantum dots Fluorescent probe Glutathione Cell culture Intracellular imaging |
DOI | 10.1016/j.snb.2017.08.170 |
收录类别 | SCI |
语种 | 英语 |
资助项目 | Ministry of Science and Technology of China[2014DFA31890] ; National Natural Science Foundation of China[21771092] |
WOS研究方向 | Chemistry ; Electrochemistry ; Instruments & Instrumentation |
WOS类目 | Chemistry, Analytical ; Electrochemistry ; Instruments & Instrumentation |
WOS记录号 | WOS:000414319900064 |
出版者 | ELSEVIER SCIENCE SA |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | https://ir.lut.edu.cn/handle/2XXMBERH/32804 |
专题 | 石油化工学院 |
通讯作者 | Qin, Wenwu |
作者单位 | 1.Lanzhou Univ, Coll Chem & Chem Engn, Key Lab Nonferrous Met Chem & Resources Utilizat, Lanzhou 730000, Gansu, Peoples R China 2.Lanzhou Univ, Coll Chem & Chem Engn, State Key Lab Appl Organ Chem, Lanzhou 730000, Gansu, Peoples R China 3.Lanzhou Univ Technol, Coll Petrochem Technol, Lanzhou 730050, Gansu, Peoples R China |
推荐引用方式 GB/T 7714 | Ma, Hong,Li, Xinran,Liu, Xiaoyu,et al. Fluorescent glutathione probe based on MnO2-Si quantum dots nanocomposite directly used for intracellular glutathione imaging[J]. SENSORS AND ACTUATORS B-CHEMICAL,2018,255:1687-1693. |
APA | Ma, Hong.,Li, Xinran.,Liu, Xiaoyu.,Deng, Min.,Wang, Xudong.,...&Qin, Wenwu.(2018).Fluorescent glutathione probe based on MnO2-Si quantum dots nanocomposite directly used for intracellular glutathione imaging.SENSORS AND ACTUATORS B-CHEMICAL,255,1687-1693. |
MLA | Ma, Hong,et al."Fluorescent glutathione probe based on MnO2-Si quantum dots nanocomposite directly used for intracellular glutathione imaging".SENSORS AND ACTUATORS B-CHEMICAL 255(2018):1687-1693. |
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