Lanzhou University of Technology Institutional Repository （LUT_IR）
| Photocatalytic degradation kinetics and mechanism of antivirus drug-lamivudine in TiO2 dispersion | |
An, Taicheng1; An, Jibin1,2,4; Yang, Hai1,4; Li, Guiying1; Feng, Huixia2 ; Nie, Xiangping3
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| 2011-12-15 | |
| Source Publication | Journal of Hazardous Materials
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| ISSN | 03043894 |
| Volume | 197Pages:229-236 |
| Abstract | Photocatalytic degradation kinetics of antivirus drug-lamivudine in aqueous TiO2 dispersions was systematically optimized by both single-variable-at-a-time and central composite design based on the response surface methodology. Three variables, TiO2 content, initial pH and lamivudine concentration, were selected to determine the dependence of degradation efficiencies of lamivudine on independent variables. Response surface methodology modeling results indicated that degradation efficiencies of lamivudine were highly affected by TiO2 content and initial lamivudine concentration. The highest degradation efficiency was achieved at suitable amount of TiO2 and with maintaining initial lamivudine concentration to a minimum. In addition, the contribution experiments of various primary reactive species produced during the photocatalysis were investigated with the addition of different scavengers and found that hydroxyl radicals was the major reactive species involved in lamivudine degradation in aqueous TiO2. Six degradation intermediates were identified using HPLC/MS/MS, and photocatalytic degradation mechanism of lamivudine was proposed by utilizing collective information from both experimental results of HPLC/MS/MS, ion chromatography as well as total organic carbon and theoretical data of frontier electron densities and point charges. © 2011 Elsevier B.V. |
| Keyword | Computer viruses Dispersions Efficiency Enzyme kinetics Ion chromatography Kinetics Mechanisms Organic carbon Oxide minerals Surface properties Titanium dioxide Central composite designs Degradation efficiency Degradation intermediates Frontier electron densities Lamivudine Photo catalytic degradation Photocatalytic degradation mechanism Response surface methodology |
| DOI | 10.1016/j.jhazmat.2011.09.077 |
| Indexed By | EI ; SCIE |
| Language | 英语 |
| WOS Research Area | Engineering ; Environmental Sciences & Ecology |
| WOS Subject | Engineering, Environmental ; Environmental Sciences |
| WOS ID | WOS:000298200400029 |
| Publisher | Elsevier B.V., Netherlands |
| EI Accession Number | 20114814568627 |
| EI Keywords | Degradation |
| EI Classification Number | 482.2 Minerals ; 601.3 Mechanisms ; 801 Chemistry ; 802.2 Chemical Reactions ; 804.1 Organic Compounds ; 804.2 Inorganic Compounds ; 913.1 Production Engineering ; 931 Classical Physics ; Quantum Theory ; Relativity ; 951 Materials Science |
| Document Type | 期刊论文 |
| Identifier | https://ir.lut.edu.cn/handle/2XXMBERH/150278 |
| Collection | 教务处（创新创业学院） |
| Affiliation | 1.State Key Laboratory of Organic Geochemistry, Guangdong Key Laboratory of Environmental Resources Utilization and Protection, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, China; 2.College of Petrochemical Technology, Lanzhou University of Technology, Lanzhou 730050, China; 3.Institute of Hydrobiology, Jinan University, Guangzhou 510632, China; 4.Graduate School of Chinese Academy of Sciences, Beijing 100049, China |
| Recommended Citation GB/T 7714 | An, Taicheng,An, Jibin,Yang, Hai,et al. Photocatalytic degradation kinetics and mechanism of antivirus drug-lamivudine in TiO2 dispersion[J]. Journal of Hazardous Materials,2011,197:229-236. |
| APA | An, Taicheng,An, Jibin,Yang, Hai,Li, Guiying,Feng, Huixia,&Nie, Xiangping.(2011).Photocatalytic degradation kinetics and mechanism of antivirus drug-lamivudine in TiO2 dispersion.Journal of Hazardous Materials,197,229-236. |
| MLA | An, Taicheng,et al."Photocatalytic degradation kinetics and mechanism of antivirus drug-lamivudine in TiO2 dispersion".Journal of Hazardous Materials 197(2011):229-236. |
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