Photocatalytic degradation kinetics and mechanism of antivirus drug-lamivudine in TiO2 dispersion

doi:10.1016/j.jhazmat.2011.09.077

	Photocatalytic degradation kinetics and mechanism of antivirus drug-lamivudine in TiO2 dispersion
	An, Taicheng 1,2; An, Jibin 1,2,3,5; Yang, Hai 1,2,5; Li, Guiying 1,2; Feng, Huixia3 ; Nie, Xiangping 4
	2011-12-15
发表期刊	Journal of Hazardous Materials
ISSN	03043894
卷号	197 页码:229-236
摘要	Photocatalytic degradation kinetics of antivirus drug-lamivudine in aqueous TiO2 dispersions was systematically optimized by both single-variable-at-a-time and central composite design based on the response surface methodology. Three variables, TiO2 content, initial pH and lamivudine concentration, were selected to determine the dependence of degradation efficiencies of lamivudine on independent variables. Response surface methodology modeling results indicated that degradation efficiencies of lamivudine were highly affected by TiO2 content and initial lamivudine concentration. The highest degradation efficiency was achieved at suitable amount of TiO2 and with maintaining initial lamivudine concentration to a minimum. In addition, the contribution experiments of various primary reactive species produced during the photocatalysis were investigated with the addition of different scavengers and found that hydroxyl radicals was the major reactive species involved in lamivudine degradation in aqueous TiO2. Six degradation intermediates were identified using HPLC/MS/MS, and photocatalytic degradation mechanism of lamivudine was proposed by utilizing collective information from both experimental results of HPLC/MS/MS, ion chromatography as well as total organic carbon and theoretical data of frontier electron densities and point charges. © 2011 Elsevier B.V.
关键词	Computer viruses Dispersions Efficiency Enzyme kinetics Ion chromatography Kinetics Mechanisms Organic carbon Oxide minerals Surface properties Titanium dioxide Central composite designs Degradation efficiency Degradation intermediates Frontier electron densities Lamivudine Photo catalytic degradation Photocatalytic degradation mechanism Response surface methodology
DOI	10.1016/j.jhazmat.2011.09.077
收录类别	EI ; SCIE
语种	英语
WOS研究方向	Engineering ; Environmental Sciences & Ecology
WOS类目	Engineering, Environmental ; Environmental Sciences
WOS记录号	WOS:000298200400029
出版者	Elsevier B.V., Netherlands
EI入藏号	20114814568627
EI主题词	Degradation
EI分类号	482.2 Minerals ; 601.3 Mechanisms ; 801 Chemistry ; 802.2 Chemical Reactions ; 804.1 Organic Compounds ; 804.2 Inorganic Compounds ; 913.1 Production Engineering ; 931 Classical Physics ; Quantum Theory ; Relativity ; 951 Materials Science
引用统计	被引频次：133[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://ir.lut.edu.cn/handle/2XXMBERH/150278
专题	教务处（创新创业学院）
通讯作者	An, Taicheng
作者单位	1.Chinese Acad Sci, Guangzhou Inst Geochem, State Key Lab Organ Geochem, Guangzhou 510640, Guangdong, Peoples R China; 2.Chinese Acad Sci, Guangzhou Inst Geochem, Guangdong Key Lab Environm Resources Utilizat & P, Guangzhou 510640, Guangdong, Peoples R China; 3.Lanzhou Univ Technol, Coll Petrochem Technol, Lanzhou 730050, Peoples R China; 4.Jinan Univ, Inst Hydrobiol, Guangzhou 510632, Guangdong, Peoples R China; 5.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	An, Taicheng,An, Jibin,Yang, Hai,et al. Photocatalytic degradation kinetics and mechanism of antivirus drug-lamivudine in TiO2 dispersion[J]. Journal of Hazardous Materials,2011,197:229-236.
APA	An, Taicheng,An, Jibin,Yang, Hai,Li, Guiying,Feng, Huixia,&Nie, Xiangping.(2011).Photocatalytic degradation kinetics and mechanism of antivirus drug-lamivudine in TiO2 dispersion.Journal of Hazardous Materials,197,229-236.
MLA	An, Taicheng,et al."Photocatalytic degradation kinetics and mechanism of antivirus drug-lamivudine in TiO2 dispersion".Journal of Hazardous Materials 197(2011):229-236.