Estimation of biophysical properties of cell exposed to electric field

doi:10.1088/1674-1056/abc543

IR > 理学院

	Estimation of biophysical properties of cell exposed to electric field
	Zhang, Hui 1; Wang, Liyang 2; Zhang, Peijie 3; Zhang, Xiaodi 1; Ma, Jun4
	2021-03
发表期刊	CHINESE PHYSICS B
ISSN	1674-1056
卷号	30 期号:3
摘要	Excitable media, such as cells, can be polarized and magnetized in the presence of an external electromagnetic field. In fact, distinct geometric deformation can be induced by the external electromagnetic field, and also the capacitance of the membrane of cell can be changed to pump the field energy. Furthermore, the distribution of ion concentration inside and outside the cell can also be greatly adjusted. Based on the theory of bio-electromagnetism, the distribution of field energy and intracellular and extracellular ion concentrations in a single shell cell can be estimated in the case with or without external electric field. Also, the dependence of shape of cell on the applied electronic field is calculated. From the viewpoint of physics, the involvement of external electric field will change the gradient distribution of field energy blocked by the membrane. And the intracellular and extracellular ion concentration show a certain difference in generating time-varying membrane potential in the presence of electric field. When a constant electric field is applied to the cell, distinct geometric deformation is induced, and the cell triggers a transition from prolate to spherical and then to oblate ellipsoid shape. It is found that the critical frequency in the applied electric field for triggering the distinct transition from prolate to oblate ellipsoid shape obtains smaller value when larger dielectric constant of the cell membrane and intracellular medium, and smaller conductivity for the intracellular medium are used. Furthermore, the effect of cell deformation is estimated by analyzing the capacitance per unit area, the density of field energy, and the change of ion concentration on one side of cell membrane. The intensity of external applied electric field is further increased to detect the change of ion concentration. And the biophysical effect in the cell is discussed. So the deformation effect of cells in electric field should be considered when regulating and preventing harm to normal neural activities occurs in a nervous system.
关键词	neuron field energy membrane deformation ion concentration
DOI	10.1088/1674-1056/abc543
收录类别	SCIE
语种	英语
WOS研究方向	Physics
WOS类目	Physics, Multidisciplinary
WOS记录号	WOS:000630470200001
出版者	IOP PUBLISHING LTD
EI入藏号	20211610229634
EI主题词	Cytology
EI分类号	461.2 Biological Materials and Tissue Engineering - 701 Electricity and Magnetism - 701.1 Electricity: Basic Concepts and Phenomena - 951 Materials Science
来源库	WOS
引用统计	被引频次：9[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://ir.lut.edu.cn/handle/2XXMBERH/147444
专题	理学院
通讯作者	Ma, Jun
作者单位	1.Xianyang Normal Univ, Coll Phys & Elect Engn, Xianyang 712000, Peoples R China; 2.Shaanxi Normal Univ, Coll Life Sci, Xian 710062, Peoples R China; 3.Changan Univ, Sch Highway, Xian 710064, Peoples R China; 4.Lanzhou Univ Technol, Dept Phys, Lanzhou 730050, Peoples R China
通讯作者单位	理学院
推荐引用方式 GB/T 7714	Zhang, Hui,Wang, Liyang,Zhang, Peijie,et al. Estimation of biophysical properties of cell exposed to electric field[J]. CHINESE PHYSICS B,2021,30(3).
APA	Zhang, Hui,Wang, Liyang,Zhang, Peijie,Zhang, Xiaodi,&Ma, Jun.(2021).Estimation of biophysical properties of cell exposed to electric field.CHINESE PHYSICS B,30(3).
MLA	Zhang, Hui,et al."Estimation of biophysical properties of cell exposed to electric field".CHINESE PHYSICS B 30.3(2021).