A Mixed Micellar Liquid Chromatography with Direct Injection for Rapid Analysis of Eight Sulfonamides in Milk

doi:10.1007/s12161-020-01733-3

	A Mixed Micellar Liquid Chromatography with Direct Injection for Rapid Analysis of Eight Sulfonamides in Milk
	Duan, Xiaoyun 1,2; Liu, Xiaofeng2 ; Dong, Yue 1; Duan, Tianjiao 2; Zhang, Jing 1; He, Shujuan 1; Yang, Fatang 1; Dong, Yuming 1
	2020-03-02
发表期刊	FOOD ANALYTICAL METHODS
ISSN	1936-9751
卷号	13 期号:5 页码:1148-1158
摘要	In this work, an isocratic mixed micellar liquid chromatography method was first applied to the separation of eight sulfonamides in milk. Mixed anionic and nonionic surfactants were used as mobile phase additives. Because proteins in the milk can be dissolved by the micelles, the milk samples can be directly injected into the chromatographic system after being simply diluted 10 times with 0.1 M sodium dodecyl sulfate solution. Besides, three-phase equilibrium theory was firstly used to explain the retention mechanism of sulfonamides in the mixed micellar liquid chromatography. The optimized mobile phase was an aqueous solution (0.04 M sodium dodecyl sulfate and 0.01 M polyoxyethylene lauryl ether) containing 20 mM NaH2PO4 with 10% (v/v) of n-propanol at pH 3.0. The separation was performed on a Venusil XBP C18 column (250 x 4.6 mm, i.d., 5 mu m). The proposed mixed micellar liquid chromatography method was validated in terms of linear ranges (20-2500 mu g/L), limit of detections (1.9-8.0 mu g/L), limit of quantitations (6.1-27 mu g/L), recoveries (84-105%), intra- and inter-precisions (RSD < 6.0%, RSD < 9.3%). The established method, which is rapid, low-cost, and environmentally friendly, provides an alternative way for rapid separation of sulfonamides within 15 min, and it does not require the complex gradient elution.
关键词	Sulfonamides Micellar liquid chromatography Milk Sample preparation Retention mechanism
DOI	10.1007/s12161-020-01733-3
收录类别	SCI
语种	英语
WOS研究方向	Food Science & Technology
WOS类目	Food Science & Technology
WOS记录号	WOS:000517683100002
出版者	SPRINGER
引用统计	被引频次：7[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://ir.lut.edu.cn/handle/2XXMBERH/60008
专题	生命科学与工程学院
通讯作者	Dong, Yuming
作者单位	1.Lanzhou Univ, Sch Pharm, Lanzhou, Peoples R China 2.Lanzhou Univ Technol, Sch Life Sci & Engn, Lanzhou, Peoples R China
第一作者单位	生命科学与工程学院
推荐引用方式 GB/T 7714	Duan, Xiaoyun,Liu, Xiaofeng,Dong, Yue,et al. A Mixed Micellar Liquid Chromatography with Direct Injection for Rapid Analysis of Eight Sulfonamides in Milk[J]. FOOD ANALYTICAL METHODS,2020,13(5):1148-1158.
APA	Duan, Xiaoyun.,Liu, Xiaofeng.,Dong, Yue.,Duan, Tianjiao.,Zhang, Jing.,...&Dong, Yuming.(2020).A Mixed Micellar Liquid Chromatography with Direct Injection for Rapid Analysis of Eight Sulfonamides in Milk.FOOD ANALYTICAL METHODS,13(5),1148-1158.
MLA	Duan, Xiaoyun,et al."A Mixed Micellar Liquid Chromatography with Direct Injection for Rapid Analysis of Eight Sulfonamides in Milk".FOOD ANALYTICAL METHODS 13.5(2020):1148-1158.