The role of aryl hydrocarbon receptor in bone remodeling

doi:10.1016/j.pbiomolbio.2017.12.005

	The role of aryl hydrocarbon receptor in bone remodeling
	Yu, Haitao 1,6; Jiang, Lili2 ; Wan, Bo 3; Zhang, Wei 4; Yao, Liqiong 1; Che, Tuanjie 5; Gan, Chao 1; Su, Na 1; He, Jinchun 1; Huang, Jintian 6
	2018-05
发表期刊	PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY
ISSN	0079-6107
卷号	134 页码:44-49
摘要	Bone remodeling is a persistent process for maintaining skeletal system homeostasis, and it depends on the dynamic equilibrium between bone-forming osteoblasts and bone-resorbing osteoclasts. Aryl hydrocarbon receptor (Ahr), a ligand-activated transcription factor, plays a pivotal role in regulating skeletal system. In order to better understand the role of Ahr in bone remodeling, we focused on bone remodeling characteristic, and the effects of Ahr on bone formation and differentiation, which suggest that Ahr is a critical control factor in the process of bone remodeling. Moreover, we discussed the impacts of Ahr on several signaling pathways related to bone remodeling, hoping to provide a theoretical basis to improve bone remodeling. (C) 2017 Published by Elsevier Ltd.
关键词	Aryl hydrocarbon receptor Bone formation Bone differentiation NF-kappa B signaling pathway Wnts signaling pathway MAPK signaling pathway
DOI	10.1016/j.pbiomolbio.2017.12.005
收录类别	SCI ; SCIE
语种	英语
资助项目	Youth Science and Technology Fund Project of Gansu Province[1606RJYA305]
WOS研究方向	Biochemistry & Molecular Biology ; Biophysics
WOS类目	Biochemistry & Molecular Biology ; Biophysics
WOS记录号	WOS:000430771900004
出版者	PERGAMON-ELSEVIER SCIENCE LTD
引用统计	被引频次：20[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://ir.lut.edu.cn/handle/2XXMBERH/32668
专题	材料科学与工程学院
通讯作者	Yu, Haitao
作者单位	1.Lanzhou Univ, Hosp 1, Dept Clincal Lab, West Rd 1 East Hills, Lanzhou 730000, Gansu, Peoples R China; 2.Lanzhou Univ Technol, Sch Mat Sci & Technol, Langongping Rd, Lanzhou 730050, Gansu, Peoples R China; 3.Lanzhou Univ, Hosp 2, Dept Endocrinol & Metab 3 & 4, 82 Cuiyingmen, Lanzhou 730000, Gansu, Peoples R China; 4.Lanzhou Univ, Hosp 1, Cental Lab, West Rd 1 East Hills, Lanzhou 730000, Gansu, Peoples R China; 5.Gansu Key Lab Funct Genom & Mol Diag, East Rd 110 Nanhe Yantan, Lanzhou 730000, Gansu, Peoples R China; 6.Lanzhou Univ, Clin Coll 1, West Rd 1 East Hills, Lanzhou 730000, Gansu, Peoples R China
推荐引用方式 GB/T 7714	Yu, Haitao,Jiang, Lili,Wan, Bo,et al. The role of aryl hydrocarbon receptor in bone remodeling[J]. PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY,2018,134:44-49.
APA	Yu, Haitao.,Jiang, Lili.,Wan, Bo.,Zhang, Wei.,Yao, Liqiong.,...&Zhang, Yiheng.(2018).The role of aryl hydrocarbon receptor in bone remodeling.PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY,134,44-49.
MLA	Yu, Haitao,et al."The role of aryl hydrocarbon receptor in bone remodeling".PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY 134(2018):44-49.

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